每周论坛之十（总第158期）：胡玉正（美国卫生研究院），2017年11月23日上午

每周论坛之十（总第158期）

报告人：胡玉正  博士

报告人单位：美国卫生研究院药物滥用研究所(NIDA/NIH)

题目：The Application of Multimodal Neural Imaging Techniques in the Study of Compulsive Behavior of Addiction

时间：2017年11月23日 （周四，9:00-10:00）

地点：太阳集团官网东校园太阳成集团tyc151cc（南学院楼C座）305

报告简介：

Substance use disorder (SUD), also known as drug addiction, constitutes a major public health problem, and is associated with high rates of crime, recidivism, and mortality. Understanding the neural circuit plasticity that occurs during the transition from initial drug exposure and reinforced drug taking, to compulsive drug taking behaviors (often followed by repetitive withdrawals from and relapses to the drug) is critically important in the development of more efficacious treatments for SUDs. Using resting-state fMRI, we recently identified distinct “go” and “stop” brain circuits, the imbalance of which was associated with compulsive behaviors of addiction in human drug users. Based upon these findings, a longitudinal study was designed using animal model to examine the causal relationships between drug taking, neural circuitry changes, and behavior alterations in addiction. A neuromodulation-based strategy is proposed for the treatment of addiction and related mental disorders.

报告人简介：

胡玉正，男，美国卫生研究院药物滥用研究所研究院(Research Fellow)。研究方向为使用多模态神经影像（功能磁共振成像[fMRI], 弥散张量成像[DTI], 波普成像[MRS]）和神经调节技术（经颅磁刺激[TMS]，光遗传学技术[Optogenetics]）等技术在系统水平和细胞水平从学习、奖赏、认知、情绪等方面研究成瘾行为的脑机制。近五年来以第一或共同第一作者在JAMA Psychiatry, Brain, Journal of Neuroscience, Human Brain Mapping等国际期刊发表论文。